Development and evaluation of a novel fluorescent chiral derivatization reagent DBD-S-M-Pro: first observation of four chiral amino acids in human hair

Author:

Wang Xin1,Sun Xiaoqi1,Jin Yueying1,Cheng Shengyu1,Han Yu1,Zhang Minghui1,Zhang Lingli1,Li Xi-Ling1,Xu Chun-Yan2,Min Jun Zhe1ORCID

Affiliation:

1. Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Department of Pharmaceutical Analysis, College of Pharmacy, Yanbian University, Yanji 133002, Jilin Province, China

2. Medical College, Dalian University, Dalian, Liaoning, China

Abstract

A new fluorescent chiral probe namely DBD-S-M-Pro was developed to sensitively and selectively determine free chiral amino acids in human hair by C18 column on UPLC-FL.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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