A chitosan-coated PCL/nano-hydroxyapatite aerogel integrated with a nanofiber membrane for providing antibacterial activity and guiding bone regeneration

Author:

Deng Xinyuan1ORCID,Yu Chenghao2,Zhang Xiaopei12,Tang Xunmeng1,Guo Qingxia3,Fu Manfei2,Wang Yuanfei4,Fang Kuanjun15,Wu Tong123ORCID

Affiliation:

1. Shandong Key Laboratory of Medical and Health Textile Materials, College of Textile & Clothing, Collaborative Innovation Center for Eco-textiles of Shandong Province and the Ministry of Education, Qingdao 266071, China

2. The Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao 266071, China

3. Institute of Neuroregeneration & Neurorehabilitation, Department of Pathophysiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China

4. Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, China

5. Laboratory for Manufacturing Low Carbon and Functionalized Textiles in the Universities of Shandong Province, Qingdao, State Key Laboratory for Biofibers and Eco-Textiles, Qingdao University, Qingdao 266071, China

Abstract

A chitosan-coated PCL/nano-hydroxyapatite aerogel was integrated with a nanofiber membrane for constructing a GBR material. Such a material can serve as a barrier and exhibit promising potential in terms of antibacterial properties and guidance of bone regeneration.

Funder

Natural Science Foundation of Shandong Province

Taishan Scholar Project of Shandong Province

Key Technology Research and Development Program of Shandong

China Association for Science and Technology

Qingdao Key Health Discipline Development Fund

Publisher

Royal Society of Chemistry (RSC)

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