Biomimetic pheomelanin to unravel the electronic, molecular and supramolecular structure of the natural product

Author:

Cao Wei123,Mao Haochuan14,McCallum Naneki C.1,Zhou Xuhao1ORCID,Sun Hao1235ORCID,Sharpe Christopher2ORCID,Korpanty Joanna1,Hu Ziying1,Ni Qing Zhe6ORCID,Burkart Michael D.6ORCID,Shawkey Matthew D.7,Wasielewski Michael R.14ORCID,Gianneschi Nathan C.1236ORCID

Affiliation:

1. Department of Chemistry, Northwestern University, Evanston, Illinois, 60208, USA

2. Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois, 60208, USA

3. Department of Biomedical Engineering, Department of Pharmacology, International Institute for Nanotechnology, Simpson-Querrey Institute, Chemistry of Life Processes Institute, Lurie Cancer Center, Northwestern University, Evanston, Illinois, 60208, USA

4. Institute for Sustainability and Energy at Northwestern University, Evanston, Illinois, 60208, USA

5. Department of Chemistry and Chemical & Biomedical Engineering, Tagliatela College of Engineering, University of New Haven, West Haven, Connecticut, 06516, USA

6. Department of Chemistry & Biochemistry, University of California, San Diego, La Jolla, California, 92093, USA

7. Evolution and Optics of Nanostructures Group, Department of Biology, The University of Ghent, 9000, Ghent, Belgium

Abstract

A robust route to synthetic pheomelanin gives insight into the electronic, molecular and supramolecular structure of the natural product, further advancing our understanding of this important subfamily of melanin.

Funder

Air Force Office of Scientific Research

Multidisciplinary University Research Initiative

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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