Endonuclease IV recognizes single base mismatch on the eighth base 3′ to the abasic site in DNA strands for ultra-selective and sensitive mutant-type DNA detection-Reference-Cited by-同舟云学术

Endonuclease IV recognizes single base mismatch on the eighth base 3′ to the abasic site in DNA strands for ultra-selective and sensitive mutant-type DNA detection

Published:2018 Issue:48 Volume:8 Page:27016-27020
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Xu Jiaju¹²³⁴⁵^ORCID,Fu Yanqiao⁶⁷⁸⁹⁵,Xiao Yan¹²³⁴⁵^ORCID

Affiliation:

1. Department of Anesthesiology

2. Tongji Hospital

3. Huazhong University of Science and Technology

4. Wuhan

5. P. R. China

6. Department of Otorhinolaryngology

7. Taihe Hospital

8. Hubei University of Medicine

9. Shiyan

Abstract

Endonuclease IV discriminates single basic mismatch in +8 position towards abasic site, which enables the detection of mutations in abundance of 0.01%.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA04552F

Reference32 articles.

1. Functional SNPs of the breast cancer resistance protein ‐ therapeutic effects and inhibitor development

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5. A branch-migration based fluorescent probe for straightforward, sensitive and specific discrimination of DNA mutations

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