Thiol-free multicomponent synthesis of non-racemic β-acyloxy thioethers from biocatalytically obtained chiral halohydrins-Reference-Cited by-同舟云学术

Thiol-free multicomponent synthesis of non-racemic β-acyloxy thioethers from biocatalytically obtained chiral halohydrins

Published:2024 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

López-Vidal Martín G.¹^ORCID,Lavandera Iván²^ORCID,Barra José L.³,Bisogno Fabricio R.¹^ORCID

Affiliation:

1. Departamento de Química Orgánica. Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, INFIQC-CONICET-UNC, Haya de la Torre y Medina Allende, X5000HUA Córdoba, Argentina

2. Departamento de Química Orgánica e Inorgánica. Universidad de Oviedo, Avenida Julián Clavería 8 33006, Oviedo, Spain

3. Departamento de Química Biológica Ranwel Caputto, CIQUIBIC-CONICET-UNC. Facultad de Ciencias Químicas, Universidad Nacional de Córdoba. Ciudad Universitaria, X5000HUA Córdoba, Argentina

Abstract

A novel thiol-free MCR for the mild synthesis of enantioenriched β-acetoxy sulfides using enzymatically prepared chiral halohydrins, potassium thioacetate and electrophiles is described.

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Fondo para la Investigación Científica y Tecnológica

Ministerio de Ciencia e Innovación

Secretaria de Ciencia y Tecnología - Universidad Nacional de Córdoba

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01737K

Reference45 articles.

1. Multicomponent reactions: advanced tools for sustainable organic synthesis

2. Chemistry and Biology Of Multicomponent Reactions

3. Bio-Catalysis in Multicomponent Reactions

4. Thiol-free chemoenzymatic synthesis of β-ketosulfides

5. A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Green synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives using sulfonic acid-supported magnetic covalent organic framework as a novel and reusable nanostructured catalyst;Research on Chemical Intermediates;2024-07-26