Thiol-free multicomponent synthesis of non-racemic β-acyloxy thioethers from biocatalytically obtained chiral halohydrins-Reference-Cited by-同舟云学术

Thiol-free multicomponent synthesis of non-racemic β-acyloxy thioethers from biocatalytically obtained chiral halohydrins

Published:2024 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

López-Vidal Martín G.¹^ORCID,Lavandera Iván²^ORCID,Barra José L.³,Bisogno Fabricio R.¹^ORCID

Affiliation:

1. Departamento de Química Orgánica. Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, INFIQC-CONICET-UNC, Haya de la Torre y Medina Allende, X5000HUA Córdoba, Argentina

2. Departamento de Química Orgánica e Inorgánica. Universidad de Oviedo, Avenida Julián Clavería 8 33006, Oviedo, Spain

3. Departamento de Química Biológica Ranwel Caputto, CIQUIBIC-CONICET-UNC. Facultad de Ciencias Químicas, Universidad Nacional de Córdoba. Ciudad Universitaria, X5000HUA Córdoba, Argentina

Abstract

A novel thiol-free MCR for the mild synthesis of enantioenriched β-acetoxy sulfides using enzymatically prepared chiral halohydrins, potassium thioacetate and electrophiles is described.

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Fondo para la Investigación Científica y Tecnológica

Ministerio de Ciencia e Innovación

Secretaria de Ciencia y Tecnología - Universidad Nacional de Córdoba

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01737K

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