(IPr)CuF-catalyzed α-site regiocontrolled trans-hydrofluorination of ynamides-Reference-Cited by-同舟云学术

(IPr)CuF-catalyzed α-site regiocontrolled trans-hydrofluorination of ynamides

Published:2016 Issue:32 Volume:14 Page:7746-7753
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhu Guohao¹²³⁴⁵,Qiu Shineng¹²³⁴⁵,Xi Yang¹²³⁴⁵,Ding Yao¹²³⁴⁵,Zhang Dongming¹²³⁴⁵,Zhang Rong¹²³⁴⁵,He Guangke¹²³⁴⁵,Zhu Hongjun¹²³⁴⁵

Affiliation:

1. Department of Applied Chemistry

2. College of Chemistry and Molecular Engineering

3. Nanjing Tech University

4. Nanjing 211816

5. People’ s Republic of China

Abstract

Experimental results indicate that the regioselectivity of the reaction is unexpectedly opposite to observed in the (Ph₃P)₃CuF-catalyzed hydrofluorination of ynamides, and the resulting α-fluoro products allowed for the synthesis of α-fluoro imides through further transformations.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01345G

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