Recent advances in Rh(i)-catalyzed enantioselective C–H functionalization

Author:

Zhang Yue12ORCID,Zhang Jing-Jing1ORCID,Lou Lujun1,Lin Ruofan1,Cramer Nicolai3ORCID,Wang Shou-Guo4ORCID,Chen Zhen1ORCID

Affiliation:

1. Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Key Lab of Biomass-Based Green Fuels and Chemicals, International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037, Jiangsu, China

2. Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences (Nanjing Botanical Garden Mem. Sun Yat-Sen), Nanjing 210014, Jiangsu, China

3. Institute of Chemical Sciences and Engineering (ISIC), EPFL SB ISIC LCSA, BCH 4305, 1015 Lausanne, Switzerland

4. Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, China

Abstract

This review aims to provide the most comprehensive and up-to-date summary of recent advances in Rh(i)-catalyzed enantioselective C−H functionalization highlighting diverse reaction development, chiral ligand design and mechanistic investigation.

Funder

Science, Technology and Innovation Commission of Shenzhen Municipality

Basic and Applied Basic Research Foundation of Guangdong Province

National Natural Science Foundation of China

Basic Research Program of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Reference126 articles.

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3. E. J.Corey and L.Kürti , Enantioselective Chemical Synthesis: Methods, Logic, and Practice , ed. E. J. Corey and L. Kürti , Direct Book Publishing , Dallas, TX , 2010

4. C–H functionalization logic in total synthesis

5. Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

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