Dialdehyde pectin-crosslinked and hirudin-loaded decellularized porcine pericardium with improved matrix stability, enhanced anti-calcification and anticoagulant for bioprosthetic heart valves-Reference-Cited by-同舟云学术

Dialdehyde pectin-crosslinked and hirudin-loaded decellularized porcine pericardium with improved matrix stability, enhanced anti-calcification and anticoagulant for bioprosthetic heart valves

Published:2021 Issue:22 Volume:9 Page:7617-7635
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Hu Mengyue¹,Peng Xu¹²,Zhao Yang¹,Yu Xiaoshuang¹,Cheng Can¹,Yu Xixun¹^ORCID

Affiliation:

1. College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, P.R. China

2. Experimental and Research Animal Institute, Sichuan University, Chengdu 610065, P.R. China

Abstract

A biological crosslinking agent (dialdehyde pectin) and anticoagulant (hirudin) were utilized to prepare the hirudin-loaded AP-fixed PP, achieving its fixation and multi-functionalization and the fabrication of leaflet materials of BHVs.

Funder

National Key Research and Development Program of China

Key Research and Development Program of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM01297E

Reference71 articles.

1. Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery

2. Transcatheter Aortic Valve Replacement in Patients With Multivalvular Heart Disease