Tumor-responsive nanomedicine based on Ce3+-modulated up-/downconversion dual-mode emission for NIR-II imaging-guided dynamic therapy

Author:

Wang Qiang1,Ye Jin1,Wang Jikun1,Liu Mengting1,Li Chunsheng1,Lv Wubin1,Liu Shuang1,Niu Na1ORCID,Xu Jiating123ORCID,Fu Yujie1234

Affiliation:

1. Key Laboratory of Forest Plant Ecology, Ministry of Education, College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, P. R. China

2. Engineering Research Center of Forest Bio-Preparation, Ministry of Education, Northeast Forestry University, Harbin 150040, P. R. China

3. Heilongjiang Provincial Key Laboratory of Ecological Utilization of Forestry-Based Active Substances, Northeast Forestry University, Harbin, 150040, P. R. China

4. Advanced Innovation Center for Tree Breeding by Molecular Design, College of Forestry, Beijing Forestry University, Beijing 100083, P. R. China

Abstract

The lanthanide-doped nanoparticles with upconversion and NIR-II downconversion dual-mode emissions were coated with copper and manganese silicate nanospheres and modified with sodium alginate for NIR-II imaging and dynamic therapy.

Funder

China Postdoctoral Science Foundation

Higher Education Discipline Innovation Project

Natural Science Foundation of Heilongjiang Province

Heilongjiang Provincial Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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