Protein localization vector propagation: a method for improving the accuracy of drug repositioning-Reference-Cited by-同舟云学术

Protein localization vector propagation: a method for improving the accuracy of drug repositioning

Published:2015 Issue:7 Volume:11 Page:2096-2102
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Yeu Yunku¹²³⁴,Yoon Youngmi⁵⁶⁷⁴,Park Sanghyun¹²³⁴

Affiliation:

1. Department of Computer Science

2. Yonsei Univertity

3. SeoDaeMun-Gu

4. Republic of Korea

5. Department of Computer Engineering

6. Gachon University

7. Seongnam-si

Abstract

Protein's subcellular localization data were propagated through a PPI network, and the propagated information improved the accuracy of a computational drug–target (disease) prediction.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MB/C5MB00306G

Reference32 articles.

1. The productivity crisis in pharmaceutical R&D

2. In silico drug repositioning – what we need to know

3. In silico repositioning of approved drugs for rare and neglected diseases

4. Drug repositioning for orphan diseases

5. Transcriptional data: a new gateway to drug repositioning?

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