New 3,4,5-trisubstituted isoxazole derivatives with potential biological properties-Reference-Cited by-同舟云学术

New 3,4,5-trisubstituted isoxazole derivatives with potential biological properties

Published:2015 Issue:6 Volume:39 Page:4295-4307
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Bustos Carlos¹²³⁴,Molins Elies⁵⁶⁷⁸,Cárcamo Juan-Guillermo⁹²³⁴,Aguilar Marcelo N.⁹²³⁴,Sánchez Christian¹²³⁴,Moreno-Villoslada Ignacio¹²³⁴,Nishide Hiroyuki¹⁰¹¹¹²¹³¹⁴,Mesías-Salazar Angela¹²³⁴,Zarate Ximena¹⁵¹⁶¹⁷⁴,Schott Eduardo¹⁸¹⁹¹⁷⁴

Affiliation:

1. Instituto de Ciencias Químicas

2. Universidad Austral de Chile

3. Valdivia

4. Chile

5. Institut de Ciència de Materials de Barcelona (ICMAB-CSIC)

6. Campus de la Universitat Autònoma de Barcelona

7. 08193 Bellaterra

8. Spain

9. Instituto de Bioquímica y Microbiología

10. Department of Applied Chemistry

11. School of Science and Engineering

12. Waseda University

13. Tokyo 169-8555

14. Japan

15. Dirección de Postgrado e Investigación

16. Universidad Autónoma de Chile

17. Santiago

18. Laboratorio de Bionanotecnologia

19. Universidad Bernardo O'Higgins

Abstract

Eighteen new isoxazole derivatives were synthesized and fully characterized. Their biological activity against Bcl-2, Bax and p21^WAF-1 was tested.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NJ/C4NJ02427C

Reference53 articles.

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2. 5-(4-Chlorophenyl)-4-methyl-3-(1-(2- phenylethyl)piperidin-4-yl)isoxazole: A Potent, Selective Antagonist at Human Cloned Dopamine D4 Receptors

3. Novel Class of Potent 4-Arylalkyl Substituted 3-Isoxazolol GABAA Antagonists: Synthesis, Pharmacology, and Molecular Modeling

4. Synthesis and Pharmacological Activities of Novel 3-(Isoxazol-3-yl)-quinazolin-4(3H)-one Derivatives

5. SYNTHESIS OF PYRAZOLONES AND ISOXAZOLES AS POTENTIAL ANTIMICROBIAL AGENTS

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