AIE-based gold nanostar-berberine dimer nanocomposites for PDT and PTT combination therapy toward breast cancer

Author:

Li Rong-Tian1,Chen Ming1,Yang Zi-Chuan1,Chen Yong-Jian1,Huang Nai-Han1,Chen Wen-Hua2ORCID,Chen Jun1,Chen Jin-Xiang1ORCID

Affiliation:

1. NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, Guangdong, China

2. School of Biotechnology and Health Sciences, International Healthcare Innovation Institute (Jiangmen), Wuyi University, 529040, Jiangmen, China

Abstract

We have developed a series of berberine-based dimers with notable AIE properties to interact with pre-designed gold nanostar to achieve synergistic treatment amongst chemo- and photothermal- and photodynamic therapies for breast cancer.

Funder

Guangdong Science and Technology Department

Guangzhou Science and Technology Program key projects

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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