Development of a pH-sensitive functionalized metal organic framework: in vitro study for simultaneous delivery of doxorubicin and cyclophosphamide in breast cancer-Reference-Cited by-同舟云学术

Development of a pH-sensitive functionalized metal organic framework: in vitro study for simultaneous delivery of doxorubicin and cyclophosphamide in breast cancer

Published:2021 Issue:53 Volume:11 Page:33723-33733
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Singh Ragini¹,Kumar Binayak¹,Sahu Ram Krishna¹,Kumari Soni¹,Jha Chandan Bhogendra²,Singh Nahar³,Mathur Rashi²,Hedau Suresh T.¹^ORCID

Affiliation:

1. Division of Molecular Oncology, ICMR-National Institute of Cancer Prevention and Research, I-7, Sector 39, Gautam Buddha Nagar, Noida-201301, U.P., India

2. Division of Cyclotron and Radiopharmaceutical Sciences, Institute of Nuclear Medicine and Allied Sciences, Defense Research and Development Organization, Brig. S.K. Mazumdar Marg, Delhi 110054, India

3. CSIR-National Physical Laboratory, New Delhi 110012, India

Abstract

Exploration of an efficient dual-drug based nanocarrier with high drug loading capacity, specific targeting properties, and long-term stability is highly desirable in cancer therapy.

Funder

Indian Council of Medical Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA04591A

Reference77 articles.

1. Dual-drug delivery based charge-conversional polymeric micelles for enhanced cellular uptake and combination therapy

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3. Significant differences in the biological activity of mononuclear Cu(ii) and Ni(ii) complexes with the polyquinolinyl ligand