A cationic copolymer as a cocatalyst for a peroxidase-mimicking heme-DNAzyme-Reference-Cited by-同舟云学术

A cationic copolymer as a cocatalyst for a peroxidase-mimicking heme-DNAzyme

Published:2021 Issue:18 Volume:9 Page:6142-6152
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Araki Haruka¹,Hagiwara Shota¹,Shinomiya Ryosuke¹,Momotake Atsuya¹,Kotani Hiroaki¹^ORCID,Kojima Takahiko¹^ORCID,Ochiai Takuro²,Shimada Naohiko²,Maruyama Atsushi²^ORCID,Yamamoto Yasuhiko¹³^ORCID

Affiliation:

1. Department of Chemistry, University of Tsukuba, Tsukuba 305-8571, Japan

2. School of Life Science and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan

3. Tsukuba Research Center for Energy Materials Science (TREMS), University of Tsukuba, Tsukuba 305-8571, Japan

Abstract

Heme binds to a parallel-stranded G-quadruplex DNA to form a peroxidase-mimicking heme-DNAzyme. We found that a polymer with protonated amino groups can act as a cocatalyst for the heme-DNAzyme in the oxidation catalysis.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Japan Agency for Medical Research and Development

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00949D

Reference62 articles.