An experimental and computational study of new spiro-barbituric acid pyrazoline scaffolds: restricted rotation <i>vs.</i> annular tautomerism-Reference-Cited by-同舟云学术

An experimental and computational study of new spiro-barbituric acid pyrazoline scaffolds: restricted rotation vs. annular tautomerism

Published:2022 Issue:15 Volume:46 Page:7242-7252
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Alizadeh Abdolali¹^ORCID,Bagherinejad Akram¹,Kayanian Jasmine¹,Vianello Robert²^ORCID

Affiliation:

1. Department of Chemistry, Tarbiat Modares University, P. O. Box 14115-175, Tehran, Iran

2. Laboratory for the Computational Design and Synthesis of Functional Materials, Department of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička 54, 10000 Zagreb, Croatia

Abstract

A regioselective [3+2] cycloaddition (32CA) reaction to synthesize unsymmetric spiro-barbituric pyrazolines containing a chromone or phenolic pyrazole moiety was achieved, providing good to excellent yields.

Funder

Tarbiat Modares University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D1NJ06208E

Reference73 articles.

1. Advances in Spirocyclic Hybrids: Chemistry and Medicinal Actions

2. Synthesis, hypnotic properties and molecular modeling studies of 1,2,7,9-tetraaza-spiro[4.5]dec-2-ene-6,8,10-triones

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