Distinct optical and kinetic responses from E/Z isomers of caspase probes with aggregation-induced emission characteristics-Reference-Cited by-同舟云学术

Distinct optical and kinetic responses from E/Z isomers of caspase probes with aggregation-induced emission characteristics

Published:2014 Issue:27 Volume:2 Page:4363-4370
ISSN:2050-750X
Container-title:J. Mater. Chem. B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Liang Jing¹²³,Shi Haibin¹²³,Kwok Ryan T. K.⁴⁵⁶⁷,Gao Meng⁸³,Yuan Youyong¹²³,Zhang Wenhua⁸³,Tang Ben Zhong⁴⁵⁶⁷⁹,Liu Bin¹²³⁸³

Affiliation:

1. Department of Chemical and Biomolecular Engineering

2. National University of Singapore

3. , Singapore

4. Department of Chemistry

5. Division of Biomedical Engineering and Institute of Molecular Functional Materials

6. The Hong Kong University of Science and Technology

7. Kowloon, China

8. Institute of Materials Research and Engineering

9. SCUT-HKUST Joint Research Laboratory

Abstract

A dual-labeled probe for monitoring caspase activity was designed and synthesized based on a tetraphenylethene (TPE) fluorogen with aggregation-induced emission characteristics and a caspase-specific Asp-Glu-Val-Asp (DFVD) peptide.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2014/TB/C4TB00405A

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