Conjugated polymer microparticles for selective cancer cell image-guided photothermal therapy
Author:
Affiliation:
1. Department of Chemical and Biomolecular Engineering
2. National University of Singapore
3. Singapore
4. Environmental Research Institute
5. Institute of Materials Research and Engineering
Abstract
We report conjugated polymers (CPs) microparticles (MPs) for selective cancer cell image-guided photothermal therapy. The CPMPs without surface functionalization can target MCF-7 cancer cells over NIH-3T3 normal cells, while nanoparticles need surface decoration to possess selectivity. Benefitting from large absorption, bright fluorescence, and efficient light-to-heat conversion of CPs, the fabricated MPs can selectively kill MCF-7 cells under NIR infrared laser irradiation.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TB/C4TB01590H
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