A new approach for the synthesis of O-glycopeptides through a combination of solid-phase glycosylation and fluorous tagging chemistry (SHGPFT)
Author:
Affiliation:
1. Institute of Materia Medica
2. Chinese Academy of Medical Sciences & Peking Union Medical College
3. Beijing 100050, P. R. China
4. Tsinghua-Peking Center for Life Sciences
5. Tsinghua University
Abstract
A new and efficient hybrid approach has been developed for the synthesis and purification of O-linked glycopeptides with high purity.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C3OB42430H
Reference45 articles.
1. Protein glycosylation. Structural and functional aspects
2. Glycobiology: Toward Understanding the Function of Sugars
3. Chemical Glycobiology
4. Glycoprotein Synthesis: An Update
5. Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research
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2. A novel macroreticular-type fluorous polystyrene resin and its application to the synthesis of a 3-amino-β-carboline derivative with N-methyl-N-nitrosourea conjugation via fluorous solid-phase reaction: a comparative study of fluorous solid-, solid-, and liquid-phase reactions;Tetrahedron;2015-07
3. Solid-phase peptide synthesis: an overview focused on the preparation of biologically relevant peptides;RSC Adv.;2014
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