An easily available endoplasmic reticulum targeting near-infrared fluorescent probe for esterase imaging <i>in vitro</i> and <i>in vivo</i>-Reference-Cited by-同舟云学术

An easily available endoplasmic reticulum targeting near-infrared fluorescent probe for esterase imaging in vitro and in vivo

Published:2022 Issue:5 Volume:147 Page:789-793
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Xiang Chunbai¹²,Xiang Jingjing¹²,Yang Xing¹²,Zhu Baode³,Mo Quanyi⁴,Zhou Lihua⁴^ORCID,Gong Ping¹

Affiliation:

1. Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

3. School of Chemistry and Environmental Science, Xiangnan University, Chenzhou 423000, China

4. School of Applied Biology, Shenzhen Institute of Technology, No. 1 Jiangjunmao, Shenzhen 518116, P. R. China

Abstract

Here, we report an easily available endoplasmic reticulum-targeting near-infrared fluorescent probe (ER-CE), which can detect esterase in the endoplasmic reticulum and monitor the changes in the esterase amount in tumors in real time.

Funder

National Key Research and Development Program of China

Shenzhen Science and Technology Innovation Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D1AN02260A

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1. Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics

2. The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue