Synthesis, crystal structure, cytotoxicity and action mechanism of a Rh(iii) complex with 8-hydroxy-2-methylquinoline as a ligand-Reference-Cited by-同舟云学术

Synthesis, crystal structure, cytotoxicity and action mechanism of a Rh(iii) complex with 8-hydroxy-2-methylquinoline as a ligand

Published:2017 Issue:1 Volume:8 Page:184-190
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Zhang Yun-Liang¹²³⁴⁵,Qin Qi-Pin¹²³⁴⁵,Cao Qian-qian¹²³⁴⁵,Han Hong-Hua¹²³⁴⁵,Liu Zhu-Ling¹²³⁴⁵,Liu Yan-Cheng¹²³⁴⁵^ORCID,Liang Hong¹²³⁴⁵,Chen Zhen-Feng¹²³⁴⁵

Affiliation:

1. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources

2. School of Chemistry & Pharmaceutical Sciences

3. Guangxi Normal University

4. Guilin

5. PR China

Abstract

1 exerted its cytotoxic activity mainly via disruption of mitochondrial function, and significantly caused S phase arrest.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C6MD00462H

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