Real-time nanoscale organization of amyloid precursor protein-Reference-Cited by-同舟云学术

Real-time nanoscale organization of amyloid precursor protein

Published:2020 Issue:15 Volume:12 Page:8200-8215
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kedia Shekhar¹²³⁴,Ramakrishna Pratyush⁵⁶⁴,Netrakanti Pallavi Rao¹²³⁴,Jose Mini¹²³⁴,Sibarita Jean-Baptiste⁷⁸⁹¹⁰¹¹,Nadkarni Suhita⁵⁶⁴,Nair Deepak¹²³⁴^ORCID

Affiliation:

1. Centre for Neuroscience

2. Indian Institute of Science

3. Bangalore 560012

4. India

5. Indian Institute of Science Education and Research

6. Pune 411008

7. Université de Bordeaux

8. Institut interdisciplinaire de Neurosciences

9. Bordeaux

10. France

11. CNRS UMR 5297

Abstract

Regulatory nanodomains modulated by lateral diffusion control transient equilibrium between pools of APP within an excitatory synapse. Molecular fingerprints of these nanodomains are altered in variants of APP implicated in Alzheimer's Disease.

Funder

Science and Engineering Research Board

Indian Institute of Science

McGill University

Tata Trusts

Indian Institute of Science Education and Research Pune

Department of Biotechnology, Ministry of Science and Technology

Indian Council of Medical Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science