Site-selective bromination of sp3 C–H bonds-Reference-Cited by-同舟云学术

Site-selective bromination of sp3 C–H bonds

Published:2018 Issue:1 Volume:9 Page:100-104
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Sathyamoorthi Shyam¹²³⁴^ORCID,Banerjee Shibdas⁵⁶⁷,Du Bois J.¹²³⁴,Burns Noah Z.¹²³⁴^ORCID,Zare Richard N.¹²³⁴^ORCID

Affiliation:

1. Stanford University

2. Department of Chemistry

3. Stanford

4. USA

5. Indian Institute of Science Education and Research Tirupati

6. Tirupati-517507

7. India

Abstract

A method for converting sp³ C–H to C–Br bonds using an N-methyl sulfamate directing group is described. For all sulfamates examined, bromination occurs with high selectivity at the γ-carbon, affording a predictable method for C–H bond halogenation.

Funder

Division of Chemistry

Air Force Office of Scientific Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C7SC04611A

Reference60 articles.

1. If CH Bonds Could Talk: Selective CH Bond Oxidation

2. Ruthenium-Catalyzed C–H Hydroxylation in Aqueous Acid Enables Selective Functionalization of Amine Derivatives