Crystal nucleation and growth in a polymorphic system: Ostwald's rule, p-aminobenzoic acid and nucleation transition states-Reference-Cited by-同舟云学术

Crystal nucleation and growth in a polymorphic system: Ostwald's rule, p-aminobenzoic acid and nucleation transition states

Author:

Black J. F. B.¹²³⁴,Cardew P. T.⁵⁶⁴^ORCID,Cruz-Cabeza A. J.⁷⁸⁴^ORCID,Davey R. J.⁷⁸⁴^ORCID,Gilks S. E.⁷⁸⁴,Sullivan R. A.¹²³⁴

Affiliation:

1. AstraZeneca

2. Pharmaceutical Development

3. Macclesfield SK10 2NA

4. UK

5. Iceeto Ltd

6. Warrington WA4 3LE

7. School of Chemical Engineering and Analytical Sciences

8. University of Manchester

Abstract

Water has a magic effect on the nucleation kinetics of an aminobenzoic acid – stacking interactions baffle Ostwald's rule and offer dual pathways.

Funder

Engineering and Physical Sciences Research Council

GSK

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

Reference44 articles.

1. J. Bernstein , Polymorphism in Molecular Crystals , Oxford University Press , New York , 2002

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