Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatment-Reference-Cited by-同舟云学术

Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatment

Published:2014 Issue:12 Volume:5 Page:1789-1796
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Pan De-Si¹²³⁴,Yang Qian-Jiao¹²³⁴,Fu Xin¹²³⁴,Shan Song¹²³⁴,Zhu Jing-Zhong¹²³⁴,Zhang Kun¹²³⁴,Li Zhi-Bin¹²³⁴,Ning Zhi-Qiang¹²³⁴,Lu Xian-Ping¹²³⁴

Affiliation:

1. Shenzhen Chipscreen Biosciences Ltd.

2. BIO-Incubator

3. Shenzhen

4. P. R. China

Abstract

Tumorigenesis is maintained through a complex interplay of multiple cellular biological processes and is regulated to some extent by epigenetic control of gene expression.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MD/C4MD00350K

Reference51 articles.

1. A decade of exploring the cancer epigenome — biological and translational implications

2. Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

3. Cancer Epigenetics: From Mechanism to Therapy

4. The many roles of histone deacetylases in development and physiology: implications for disease and therapy

5. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

Cited by 51 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis, and biological activity evaluation of novel HDAC3 selective inhibitors for combination with Venetoclax against acute myeloid leukemia;European Journal of Medicinal Chemistry;2024-10

2. Design, synthesis, and in vitro biological evaluation of novel HDAC inhibitors bearing C-1 phenyl substituted tetrahydroisoquinoline Cap moiety as anti-tumor therapeutic agents;Medicinal Chemistry Research;2024-03-27

3. Noval advance of histone modification in inflammatory skin diseases and related treatment methods;Frontiers in Immunology;2024-01-03

4. Epigenetic Changes Induced by Infectious Agents in Cancer;Pathogens Associated with the Development of Cancer in Humans;2024

5. Perspectives and new aspects of histone deacetylase inhibitors in the therapy of CNS diseases;European Journal of Medicinal Chemistry;2023-10