Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy-Reference-Cited by-同舟云学术

Ultra-efficient delivery of CRISPR/Cas9 using ionic liquid conjugated polymers for genome editing-based tumor therapy

Published:2024 Issue:7 Volume:12 Page:1716-1725
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Huang Zhongming¹,Yang Tongren²,Yu Jie¹,Gao Yijian¹,Weng Yuhua²,Huang Yuanyu²,Li Shengliang¹^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China

2. School of Medical Technology (Institute of Engineering Medicine), Advanced Research Institute of Multidisciplinary Science, School of Life Science, Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, 100081, China

Abstract

Through molecular screening, ionic liquid-conjugated polymers (IL-CPs) are developed for highly efficient delivery of CRISPR/Cas9 system, which demonstrated high-performance genome editing-based tumor therapy.

Funder

National Basic Research Program of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Beijing Municipal Natural Science Foundation

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D3BM01981K

Reference50 articles.

1. The promises and pitfalls of RNA-interference-based therapeutics

2. Gene therapy - promises, problems and prospects

3. Nucleic Acid Delivery: The Missing Pieces of the Puzzle?

4. Progress in gene therapy for neurological disorders

5. Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

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