Exploiting intramolecular hydrogen bonding for the highly (Z)-selective & metal free synthesis of amide substituted β-aminoenones-Reference-Cited by-同舟云学术

Exploiting intramolecular hydrogen bonding for the highly (Z)-selective & metal free synthesis of amide substituted β-aminoenones

Published:2017 Issue:11 Volume:19 Page:2541-2545
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Subramaniam Palaniraja¹²³⁴⁵^ORCID,Ramasubbu Chandrasekaran⁶⁷³,Athiramu Selvaraj⁴⁵⁸³

Affiliation:

1. Sigma-Aldrich Chemicals Pvt. Ltd (subsidiary of Merck KGaA)

2. Bangalore-560100

3. India

4. Research and Development Center

5. Bharathiar University

6. Sai Supreme Chemicals

7. Chennai-601201

8. Coimbatore-641046

Abstract

An intramolecular hydrogen bonding directed highly stereospecific, transition metal free synthetic protocol for amide substituted β-aminoenones. High stereoselectivity, excellent yields and high purity were achieved by mere filtration without column chromatographic purification.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/GC/C7GC00909G

Reference35 articles.

1. Intramolecular Hydrogen Bonding in Medicinal Chemistry

2. Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

3. On the interactions of leflunomide and teriflunomide within receptor cavity — NMR studies and energy calculations

4. Evidence for Intramolecular N−H···O Resonance-Assisted Hydrogen Bonding in β-Enaminones and Related Heterodienes. A Combined Crystal-Structural, IR and NMR Spectroscopic, and Quantum-Mechanical Investigation

5. Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space

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