A rational design of a cancer-specific and lysosome-targeted fluorescence nanoprobe for glutathione imaging in living cells-Reference-Cited by-同舟云学术

A rational design of a cancer-specific and lysosome-targeted fluorescence nanoprobe for glutathione imaging in living cells

Published:2020 Issue:6 Volume:1 Page:1739-1744
ISSN:2633-5409
Container-title:Materials Advances
language:en
Short-container-title:Mater. Adv.

Author:

Wang Hong¹²³⁴⁵^ORCID,Zhang Peisheng¹²³⁴⁵^ORCID,Zhang Chonghua¹²³⁴⁵,Chen Shu¹²³⁴⁵,Zeng Rongjin¹²³⁴⁵,Cui Jiaxi⁶⁷⁸⁹¹⁰^ORCID,Chen Jian¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Theoretical Organic Chemistry and Function Molecule

2. Ministry of Education, Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers

3. Hunan Province College Key Laboratory of QSAR/QSPR

4. Hunan Provincial Key Lab of Advanced Materials for New Energy Storage and Conversion

5. School of Chemistry and Chemical Hunan University of Science and Technology

6. Institute of Fundamental and Frontier Sciences

7. University of Electronic Science and Technology of China

8. Chengdu

9. China

10. INM-Leibniz Institute for New Materials

Abstract

A dual-targeting (both cancer cell- and lysosome-targeting) fluorescence nanoprobe was rational designed and synthesized for the efficient imaging of lysosomal GSH in cancer cells.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

China Postdoctoral Science Foundation

Education Department of Hunan Province

State Key Laboratory of Chemo/Biosensing and Chemometrics

State Key Laboratory of Luminescent Materials and Devices

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MA/D0MA00124D

Reference68 articles.

1. Lysosomes contribute to radioresistance in cancer

2. Turn up the lysosome

3. Glutathione in Cancer Biology and Therapy

4. Metastasis: cancer cell’s escape from oxidative stress

5. Cancer cell recognition by a Cys-reactive turn-on significant enhanced fluorescent emission targeting biotin receptors

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