High denticity oxinate-linear-backbone chelating ligand for diagnostic radiometal ions [111In]In3+ and [89Zr]Zr4+-Reference-Cited by-同舟云学术

High denticity oxinate-linear-backbone chelating ligand for diagnostic radiometal ions [111In]In3+ and [89Zr]Zr4+

Published:2021 Issue:11 Volume:50 Page:3874-3886
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Southcott Lily¹²³⁴⁵^ORCID,Wang Xiaozhu¹²³⁴⁵^ORCID,Wharton Luke¹²³⁴⁵^ORCID,Yang Hua⁶⁷⁴⁵^ORCID,Radchenko Valery⁶⁷⁴⁵²,Kubeil Manja⁸⁹¹⁰¹¹^ORCID,Stephan Holger⁸⁹¹⁰¹¹^ORCID,de Guadalupe Jaraquemada-Peláez María¹²³⁴⁵^ORCID,Orvig Chris¹²³⁴⁵^ORCID

Affiliation:

1. Medicinal Inorganic Chemistry Group

2. Department of Chemistry

3. University of British Columbia

4. Vancouver

5. Canada

6. Life Sciences Division

7. TRIUMF

8. Institute of Radiopharmaceutical Cancer Research

9. Helmholtz-Zentrum Dresden Rossendorf

10. 01328 Dresden

11. Germany

Abstract

A potentially decadentate oxinate-containing ligand was synthesized and assessed through solution thermodynamics studies, concentration dependent radiolabeling and serum stability assays with [^nat/111In]In³⁺ and [^nat/89Zr]Zr⁴⁺.

Funder

Natural Sciences and Engineering Research Council of Canada

University of British Columbia

Canadian Institutes of Health Research

National Research Council Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D0DT04230G

Reference71 articles.