Cu-catalyzed cyclization to construct indoles from N-(ortho-chloromethyl)aryl carbamates and terminal alkynes via a one-pot reaction

Author:

Shi Yang12345ORCID,Wang Gangqiang12345,Wang Hang12345,Deng Bin12345,Gao Tao12345,Wang Jian12345,Guo Haibing12345,Wu Minghu12345,Sun Shaofa12345

Affiliation:

1. Hubei Key Laboratory of Radiation Chemistry and Functional Materials

2. Non-power Nuclear Technology Collaborative Innovation Center

3. School of Nuclear Technology and Chemistry & Biology

4. Hubei University of Science and Technology

5. Xianning 437100

Abstract

In this reaction, a new strategy for the synthesis of indoles from N-(ortho-chloromethyl)aryl carbamates and terminal alkynes via Cu-catalyzed coupling–cyclization has been developed.

Funder

National College Students Innovation and Entrepreneurship Training Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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