Theoretical insight into the origins of chemo- and diastereo-selectivity in the palladium-catalysed (3 + 2) cyclisation of 5-alkenyl thiazolones-Reference-Cited by-同舟云学术

Theoretical insight into the origins of chemo- and diastereo-selectivity in the palladium-catalysed (3 + 2) cyclisation of 5-alkenyl thiazolones

Published:2021 Issue:22 Volume:8 Page:6203-6214
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Qi Ting¹,Fu Shuai²,Zhang Xiang¹,Liu Ting-Hao²,Li Qing-Zhu¹,Gou Chuan¹,Li Jun-Long¹^ORCID

Affiliation:

1. Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, Sichuan, 610106, China

2. College of Chemical Engineering, Sichuan University, Chengdu, Sichuan, 610065, P.R. China

Abstract

The mechanism of the palladium-catalysed (3 + 2) cyclisation of 5-alkenyl thiazolones and VECs has been investigated from a computational perspective, and the origins of unique chemoselectivity and excellent diastereoselectivity have been disclosed.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Chengdu University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO01071A

Reference95 articles.

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