Hydroxyl group-directed, tartaric acid-catalyzed synthesis of meta-functionalized aryl ethers and phenols through domino conjugate addition/aromatization of para-quinols-Reference-Cited by-同舟云学术

Hydroxyl group-directed, tartaric acid-catalyzed synthesis of meta-functionalized aryl ethers and phenols through domino conjugate addition/aromatization of para-quinols

Published:2021 Issue:24 Volume:8 Page:6851-6856
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Guo-Shu¹,Li Jia-Hui¹,Chen Shu-Jie¹^ORCID,Lin Wen-Xia¹,Ren Hai²,Deng Dong-Sheng³^ORCID,Liu Yun-Lin¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, P.R. China

2. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, P.R. China

3. College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471934, P.R. China

Abstract

A tartaric acid-catalyzed three-component reaction of para-quinols, organoboronic acids, and alcohols affords meta-alkenylated aryl alkyl ether in good yields. In the absence of alcohols, meta-functionalized phenols could be obtained selectively.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangzhou Municipal Science and Technology Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO01078F

Reference51 articles.

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