Use multiscale simulation to explore the effects of the homodimerizations between different conformation states on the activation and allosteric pathway for the μ-opioid receptor-Reference-Cited by-同舟云学术

Use multiscale simulation to explore the effects of the homodimerizations between different conformation states on the activation and allosteric pathway for the μ-opioid receptor

Published:2018 Issue:19 Volume:20 Page:13485-13496
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Zhang Xi¹²³⁴,Yuan Yuan⁵⁶⁷⁸,Wang Longrong¹²³⁴,Guo Yanzhi¹²³⁴^ORCID,Li Menglong¹²³⁴,Li Chuan⁹²³⁸,Pu Xuemei¹²³⁴

Affiliation:

1. College of Chemistry

2. Sichuan University

3. Chengdu

4. People's Republic of China

5. College of Management

6. Southwest University for Nationalities

7. Chengdu 610041

8. P. R. China

9. College of Computer Science

Abstract

Using multiscale simulation to explore the activation of a GPCR dimer.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CP/C8CP02016G

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4. A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

5. Oligomeric forms of G protein-coupled receptors (GPCRs)

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