Binding interactions of hydrophobically-modified flavonols with β-glucosidase: fluorescence spectroscopy and molecular modelling study-Reference-Cited by-同舟云学术

Binding interactions of hydrophobically-modified flavonols with β-glucosidase: fluorescence spectroscopy and molecular modelling study

Published:2023 Issue:48 Volume:13 Page:34107-34121
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chepeleva Liudmyla V.¹,Demidov Oleksii O.¹,Snizhko Arsenii D.¹,Tarasenko Dmytro O.¹^ORCID,Chumak Andrii Y.¹,Kolomoitsev Oleksii O.¹^ORCID,Kotliar Volodymyr M.¹^ORCID,Gladkov Eugene S.¹²,Kyrychenko Alexander¹²^ORCID,Roshal Alexander D.¹^ORCID

Affiliation:

1. Institute of Chemistry, V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv 61022, Ukraine

2. State Scientific Institution “Institute for Single Crystals”, National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine

Abstract

Binding interactions of fluorescent flavonols with the β-glucosidase enzyme are studied using fluorescence spectroscopy in combination with molecular docking and molecular dynamics simulations.

Funder

National Research Foundation of Ukraine

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA06276G

Reference85 articles.

1. Exploring double proton transfer: A review on photochemical features of compounds with two proton-transfer sites

2. Solvatochromic and Fluorogenic Dyes as Environment-Sensitive Probes: Design and Biological Applications

3. Fluorescence behavior of (selected) flavonols: a combined experimental and computational study

4. 4’-Nitroflavonol fluorescence: Excited state intramolecular proton transfer reaction from the non-emissive excited state

5. Donor engineering on flavonoid-based probes to enhance the fluorescence brightness in water: Design, characterization, photophysical properties, and application for cysteine detection

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