<i>In vitro</i> profiling and molecular dynamics simulation studies of berberine loaded MCM-41 mesoporous silica nanoparticles to prevent neuronal apoptosis-Reference-Cited by-同舟云学术

In vitro profiling and molecular dynamics simulation studies of berberine loaded MCM-41 mesoporous silica nanoparticles to prevent neuronal apoptosis

Published:2024 Issue:9 Volume:6 Page:2469-2486
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Singh Anurag Kumar¹^ORCID,Singh Snigdha¹,Minocha Tarun²,Yadav Sanjeev Kumar²,Narayan Reema³,Nayak Usha Yogendra³,Singh Santosh Kumar¹,Awasthi Rajendra⁴^ORCID

Affiliation:

1. Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India

2. Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi 221005, India

3. Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India

4. Department of Pharmaceutical Sciences, School of Health Sciences & Technology, UPES University, Dehradun 248007, Uttarakhand, India

Abstract

Berberine-loaded mesoporous silica nanoparticle-controlled drug release by a simple or quasi-diffusion mechanism, improving neuronal health, preventing apoptosis, and restoring mitochondrial membrane potential.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NA/D3NA01142A

Reference56 articles.

1. Modifiable Risk Factors for Brain Health and Dementia and Opportunities for Intervention: A Brief Review

2. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

3. Lipid-Coated MCM-41 Mesoporous Silica Nanoparticles Loaded with Berberine Improved Inhibition of Acetylcholine Esterase and Amyloid Formation

4. Multidisciplinary Role of Mesoporous Silica Nanoparticles in Brain Regeneration and Cancers: From Crossing the Blood–Brain Barrier to Treatment

5. Strategies for delivering therapeutics across the blood–brain barrier

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