Evaluation of O-alkyl and aryl sulfonyl aromatic and heteroaromatic amidoximes as novel potent DNA photo-cleavers-Reference-Cited by-同舟云学术

Evaluation of O-alkyl and aryl sulfonyl aromatic and heteroaromatic amidoximes as novel potent DNA photo-cleavers

Published:2016 Issue:3 Volume:15 Page:351-360
ISSN:1474-905X
Container-title:Photochemical & Photobiological Sciences
language:en
Short-container-title:Photochem. Photobiol. Sci.

Author:

Papastergiou A.¹²³⁴⁵,Perontsis S.⁶⁷⁸⁹¹⁰,Gritzapis P.¹²³⁴⁵,Koumbis A. E.¹¹⁷⁸⁹¹⁰,Koffa M.¹²³⁴⁵¹⁰,Psomas G.⁶⁷⁸⁹¹⁰,Fylaktakidou K. C.¹²³⁴⁵

Affiliation:

1. Laboratory of Organic

2. Bioorganic and Natural Product Chemistry

3. Molecular Biology and Genetics Department

4. Democritus University of Thrace

5. Alexandroupolis

6. Laboratory of Inorganic Chemistry

7. Chemistry Department

8. Aristotle University of Thessaloniki

9. Thessaloniki

10. Greece

11. Laboratory of Organic Chemistry

12. Laboratory of Cellular Biology and Cell Cycle

Abstract

O-Alkyl and aryl p-pyridine sulfonyl amidoxime derivatives are effective novel DNA photo-cleavers, generating highly efficient sulfonyloxyl radicals, able to cause a high ratio of single to double strand nicks.

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/PP/C5PP00439J

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