Application of pyrrolo-protected amino aldehydes in the stereoselective synthesis of <i>anti</i>-1,2-amino alcohols-Reference-Cited by-同舟云学术

Application of pyrrolo-protected amino aldehydes in the stereoselective synthesis of anti-1,2-amino alcohols

Published:2022 Issue:64 Volume:58 Page:8990-8993
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sauer Maria¹,Beemelmanns Christine¹²^ORCID

Affiliation:

1. Research group Chemical Biology of Microbe-Host Interactions, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute (HKI), Beutenbergstraße 11a, 07745 Jena, Germany

2. Biochemistry of Microbial Metabolism, Institute of Biochemistry, Leipzig University, Johannisallee 21-23, Leipzig 04103, Germany

Abstract

Application of the 2,5-dimethylpyrrolo unit as a protecting group in the highly diastereoselective synthesis of anti-amino alcohols (63–90% yields with up to 20 : 1 dr).

Funder

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC02317B

Reference27 articles.

1. 1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis

2. The synthesis and configurational stability of differentially protected .beta.-hydroxy-.alpha.-amino aldehydes

3. Structural absorption by barbule microstructures of super black bird of paradise feathers

4. Synthesis and Diastereoselective Reactions of N,N-Dibenzylamino Aldehydes and Related Compounds

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