Enzyme aggregation and fragmentation induced by catalysis relevant species-Reference-Cited by-同舟云学术

Enzyme aggregation and fragmentation induced by catalysis relevant species

Published:2021 Issue:36 Volume:23 Page:20709-20717
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Gentile Kayla¹,Bhide Ashlesha¹^ORCID,Kauffman Joshua¹,Ghosh Subhadip¹^ORCID,Maiti Subhabrata¹^ORCID,Adair James²,Lee Tae-Hee¹,Sen Ayusman¹^ORCID

Affiliation:

1. Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA

2. Department of Materials Science and Engineering, The Pennsylvania State University, University Park, PA 16802, USA

Abstract

Alkaline phosphatase, hexokinase, and glucose oxidase either aggregate or fragment after addition of species directly related to their catalysis. This shows that specific multimeric structures of native enzymes may not be retained during catalysis.

Funder

Air Force Office of Scientific Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP02966E

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