Photolysis of tolfenamic acid in aqueous and organic solvents: a kinetic study

Author:

Kazi Sadia Hafeez1,Sheraz Muhammad Ali1ORCID,Anwar Zubair2ORCID,Musharraf Syed Ghulam3ORCID,Ahmed Sofia1ORCID,Bano Raheela4,Mirza Tania2,Heo Kyuyoung5ORCID,Na Jun-Hee6ORCID

Affiliation:

1. Department of Pharmaceutics, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi–75340, Pakistan

2. Department of Pharmaceutical Chemistry, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi–75340, Pakistan

3. Third World Center for Science and Technology, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi–75270, Pakistan

4. Dow College of Pharmacy, Dow University of Health Sciences (Ojha Campus), Karachi, Pakistan

5. Reliability Assessment Center, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea

6. Department of Convergence System Engineering, Chungnam National University, Daejeon 34134, Republic of Korea

Abstract

The photolysis of tolfenamic acid (TA) in aqueous and organic solvents formed 17 photoproducts, of which 9 were reported for the first time.

Publisher

Royal Society of Chemistry (RSC)

Reference93 articles.

1. S.Ahmed , M. A.Sheraz and I.Ahmad , in Profiles of Drug Substances, Excipients, and Related Methodology , ed. H. G. Brittain , Academic Press, Elsevier , Cambridge, USA , 2018 , vol. 43 , pp. 255–319

2. British National Formulary (BNF) 85 , BMJ Group and Royal Pharmaceutical Society , Pharmaceutical Press , London, UK , 2023

3. Tolfenamic Acid: A Modifier of the Tau Protein and its Role in Cognition and Tauopathy

4. Tolfenamic Acid Prevents Amyloid β-induced Olfactory Bulb Dysfunction In Vivo

5. Tolfenamic Acid Attenuates 3-Nitropropionic Acid-Induced Biochemical Alteration in Mice

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