Construction of mPt/ICG-αA nanoparticles with enhanced phototherapeutic activities for multidrug-resistant bacterial eradication and wound healing

Author:

Li Lei1,Zhu Guoqing1,Xu Wencheng1,Wang Man1,Xie Yulin1,Bao Zixian2,Qi Manlin3,Gao Minghong1,Li Chunxia1ORCID

Affiliation:

1. Institute of Molecular Sciences and Engineering, Institute of Frontier and Interdisciplinary Science, Shandong University, Qingdao 266237, P. R. China

2. State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, P. R. China

3. Department of Oral Implantology, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun 130021, P. R. China

Abstract

Novel composite nanoparticles mPt/ICG-αA, which combine catalase-like, photodynamic, photothermal, and α-amylase hydrolysis properties, have been developed for multidrug-resistant bacterial eradication and wound healing.

Funder

National Natural Science Foundation of China

Taishan Scholar Foundation of Shandong Province

Natural Science Foundation of Shandong Province

Shandong University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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