Nitrile stabilized synthesis of pyrrolidine and piperidine derivatives <i>via</i> tandem alkynyl aza-Prins–Ritter reactions-Reference-Cited by-同舟云学术

Nitrile stabilized synthesis of pyrrolidine and piperidine derivatives via tandem alkynyl aza-Prins–Ritter reactions

Published:2024 Issue:3 Volume:22 Page:568-578
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Shit Sudip¹,Choudhury Chinmayee¹^ORCID,Saikia Anil K.¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

Abstract

Triflic acid-mediated protocol for the synthesis of N-(pyrrolidine-3-ylidenemethyl)acetamide and its piperidine analogue in good yields with separable Z/E isomer has been demonstrated.

Funder

Indian Institute of Technology Guwahati

Science and Engineering Research Board

CouncilofScientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01764H

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1. The first synthesis of kaitocephalin based on the structure revision

2. New Targets for Antivirals: The Ribosomal A-Site and the Factors That Interact with It

3. Cytotoxic and Antiproliferative Effects of Preussin, a Hydroxypyrrolidine Derivative from the Marine Sponge-Associated Fungus Aspergillus candidus KUFA 0062, in a Panel of Breast Cancer Cell Lines and Using 2D and 3D Cultures

4. A silicon controlled total synthesis of the antifungal agent (+)-preussin

5. Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

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