Dicalcium silicate microparticles modulate the differential expression of circRNAs and mRNAs in BMSCs and promote osteogenesis via circ_1983–miR-6931–Gas7 interaction

Author:

Zhong Wenchao12345,Li Xingyang12345,Pathak Janak L.12345ORCID,Chen Liangjiao12345,Cao Wei12345,Zhu Mingjing12345,Luo Qianting12345,Wu Antong12345,Chen Yunxin12345,Yi Lingbo675,Ma Manyuan675,Zhang Qingbin12345ORCID

Affiliation:

1. Key Laboratory of Oral Medicine

2. Guangzhou Institute of Oral Disease

3. Affiliated Stomatology Hospital of Guangzhou Medical University

4. Guangzhou

5. China

6. Health Time Gene Institute

7. Shenzhen

Abstract

Among C2S-induced differentially expressed circRNAs, circ_1983 is involved in osteogenesis via circ_1983–miR-6931–Gas7 ceRNA interaction-mediated Runx2 upregulation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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