Proteome-wide analysis of protein alterations in response to aristolochic acids in rat kidney and liver tissues

Author:

Liu Jingjing12345ORCID,Dong Wei1234,Wong Tin Yan6789ORCID,Qiu Chengchao1234,Wu Jing123410,Zhao Jian1234,Xia Jinqiang51134,Xie Shaofei51134,Song Xiaofeng1234ORCID

Affiliation:

1. Department of Biomedical Engineering

2. Nanjing University of Aeronautics and Astronautics

3. Nanjing 210016

4. China

5. The State Key Laboratory of Translational Medicine and Innovative Drug Development

6. Department of Chemical and Biological Engineering

7. The Hong Kong University of Science and Technology

8. Kowloon

9. Hong Kong

10. School of Biomedical Engineering and Informatics

11. Jiangsu Simcere pharmaceutical Co., Ltd

Abstract

For the first time aristolochic acid toxicity to different organs was investigated in a sequence-specific and proteome-wide manner.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Genetics,Molecular Biology,Biochemistry

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