Activatable near-infrared fluorescence probe for real-time imaging of PD-L1 expression in tumors

Author:

Kim Hyunjin1,Liu Maixian1,Park Chan Hyeok23,Lee Byung Il23,Jang Hyonchol23,Choi Yongdoo1ORCID

Affiliation:

1. Division of Technology Convergence, National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-Do, 10408, Republic of Korea

2. Division of Rare and Refractory Cancer, National Cancer Center, 323 Ilsan-ro, Goyang, Gyeonggi-Do, 10408, Republic of Korea

3. Department of Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, 323 Ilsan-ro, Goyang, Gyeonggi-Do, 10408, Republic of Korea

Abstract

The activatable fluorescence probe Q-Atezol demonstrates great potential as an exceptional sensor for assessing PD-L1 expression in three-dimensional cell structures and for in vivo applications.

Funder

National Cancer Center

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

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