Medicinal Au(i) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition-Reference-Cited by-同舟云学术

Medicinal Au(i) compounds targeting urease as prospective antimicrobial agents: unveiling the structural basis for enzyme inhibition

Published:2021 Issue:40 Volume:50 Page:14444-14452
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Mazzei Luca¹^ORCID,Massai Lara²,Cianci Michele³,Messori Luigi²^ORCID,Ciurli Stefano¹^ORCID

Affiliation:

1. Laboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via Giuseppe Fanin 40, I-40127 Bologna, Italy

2. Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3-13, I-50019 Sesto Fiorentino, Italy

3. Department of Agricultural, Food and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, I-60131 Ancona, Italy

Abstract

A few gold compounds were recently found to show antimicrobial properties in vitro, holding great promise for the discovery of new drugs to overcome antibiotic resistance.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT02488D

Reference61 articles.

1. Metal complexes for therapeutic applications

2. Synthesis and Structure–Activity Relationship Study of Antimicrobial Auranofin against ESKAPE Pathogens

3. Gold(III) complexes in medicinal chemistry

4. Unveiling the Potential of Transition Metal Complexes for Medicine: Translational in Situ Activation of Metal‐Based Drugs from Bench to in Vivo Applications

5. Gold compounds as therapeutic agents for human diseases

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