Four monomeric copper(ii) complexes of non-steroidal anti-inflammatory drug Ibuprofen and N-donor ligands: syntheses, characterization, crystal structures and cytotoxicity studies

Author:

Kumar Santosh1234,Garg Shipra1234,Sharma Raj Pal1234,Venugopalan Paloth1234,Tenti Lorenzo5678,Ferretti Valeria5678ORCID,Nivelle Laetitia9101112,Tarpin Michel9101112,Guillon Emmanuel1314101112

Affiliation:

1. Department of Chemistry

2. Panjab University

3. Chandigarh

4. India

5. Center for Structural Diffractometry and Department of Chemical and Pharmaceutical Sciences

6. University of Ferrara

7. Ferrara

8. Italy

9. Laboratoire Signalisation Cellulaire et Récepteurs Matriciels (SiRMa, UMR CNRS 7369MEDyC)

10. Université de Reims Champagne-Ardenne

11. F-51687 Reims Cedex 2

12. France

13. Institut de Chimie Moléculaire de Reims (ICMR, UMR CNRS 7312)

14. Groupe Chimie de Coordination

Abstract

The cytotoxic effects of four new Ibuprofen–Cu(ii) complexes were tested finding significant cytotoxicity on human melanoma cell line HT-144.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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