A supramolecular cavitand for selective chromatographic separation of peptides using LC-MS/MS: a combined in silico and experimental approach-Reference-Cited by-同舟云学术

A supramolecular cavitand for selective chromatographic separation of peptides using LC-MS/MS: a combined in silico and experimental approach

Published:2021 Issue:1 Volume:45 Page:141-146
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Mekapothula Subbareddy¹²³⁴,Wonanke A. D. Dinga¹²³⁴,Addicoat Matthew A.¹²³⁴^ORCID,Wallis John D.¹²³⁴^ORCID,Boocock David J.¹²³⁴^ORCID,Cave Gareth W. V.¹²³⁴^ORCID

Affiliation:

1. School of Science and Technology

2. Nottingham Trent University

3. Nottingham

4. UK

Abstract

The chromatographic separation of proteomic standards via a silica immobilized pillararene cavitand has been designed in silico using host–guest binding energy studies and realized experimentally to selectively interact with peptides.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D0NJ03555F

Reference38 articles.

1. Proteomics

2. Proteome and proteomics: New technologies, new concepts, and new words

3. Evaluation of Different Stationary Phases in the Separation of Inter-Cross-Linked Peptides

4. Narrow, Open, Tubular Column for Ultrahigh-Efficiency Liquid-Chromatographic Separation under Elution Pressure of Less than 50 bar

5. Trimodal Mixed Mode Chromatography That Enables Efficient Offline Two-Dimensional Peptide Fractionation for Proteome Analysis

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