Carrier-free chemo-phototherapeutic nanomedicines with endo/lysosomal escape function enhance the therapeutic effect of drug molecules in tumors-Reference-Cited by-同舟云学术

Carrier-free chemo-phototherapeutic nanomedicines with endo/lysosomal escape function enhance the therapeutic effect of drug molecules in tumors

Published:2024 Issue:27 Volume:12 Page:6703-6715
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Feng Xue¹,Brown Calum M.²,Wang Hongdi¹,Kashif Saima¹,Roberts Sam¹,Yan Li³^ORCID,Munshi Tasnim⁴^ORCID,Hands Philip J. W.²^ORCID,Zhang Wenjun⁵^ORCID,Chen Xianfeng¹^ORCID

Affiliation:

1. School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, EH9 3JL Edinburgh, UK

2. School of Engineering, Institute for Integrated Micro and Nano Systems, University of Edinburgh, The King's Buildings, EH9 3FF Edinburgh, UK

3. College of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China

4. School of Chemistry, University of Lincoln, Brayford Pool, Lincoln, Lincolnshire LN6 7TS, UK

5. Department of Materials Science and Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon Tong, Hong Kong SAR

Abstract

This study develops synergistic carrier-free nanodrugs, characterized by high drug loading and the capacity for rapid endo/lysosomal escape. We investigate the impact of MPN layer thickness on the chemo-phototherapeutic efficacy of these nanodrugs.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB00465E

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