Stereoselective synthesis of γ-hydroxynorvaline through combination of organo- and biocatalysis-Reference-Cited by-同舟云学术

Stereoselective synthesis of γ-hydroxynorvaline through combination of organo- and biocatalysis

Published:2014 Issue:99 Volume:50 Page:15669-15672
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Simon Robert C.¹²³⁴,Busto Eduardo¹²³⁴,Schrittwieser Joerg H.¹²³⁴,Sattler Johann H.⁵⁶,Pietruszka Jörg⁷⁸⁹,Faber Kurt¹²³⁴,Kroutil Wolfgang¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of Graz

3. NAWI Graz

4. A-8010-Graz, Austria

5. Austrian Centre of Industrial Biotechnology (ACIB)

6. 8010 Graz, Austria

7. Institut für Bioorganische Chemie

8. Heinrich-Heine-Universität Düsseldorf im Forschungszentrum Jülich

9. D-52426-Jülich, Germany

Abstract

Stereoselective synthesis of all four diastereomers of PMP-protected γ-hydroxynorvaline via an organocatalytic Mannich reaction and an enzymatic ketone reduction.

Funder

European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC06230B

Reference49 articles.

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2. Combining transition metal catalysis and organocatalysis – an update

3. Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis

4. Bifunctional organo/metal cooperative catalysis with cinchona alkaloid scaffolds

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