Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer?-Reference-Cited by-同舟云学术

Proteome-wide analysis of human disease mutations in short linear motifs: neglected players in cancer?

Published:2014 Issue:10 Volume:10 Page:2626-2642
ISSN:1742-206X
Container-title:Mol. BioSyst.
language:en
Short-container-title:Mol. BioSyst.

Author:

Uyar Bora¹²³,Weatheritt Robert J.⁴⁵⁶⁷⁸,Dinkel Holger¹²³,Davey Norman E.¹²³⁹¹⁰,Gibson Toby J.¹²³

Affiliation:

1. Structural and Computational Biology Unit

2. European Molecular Biology Laboratory

3. Heidelberg, Germany

4. MRC Laboratory of Molecular Biology

5. Cambridge CB2 0QH, UK

6. Banting and Best Department of Medical Research and Donnelly Centre

7. University of Toronto

8. Toronto, Canada

9. Department of Physiology

10. University of California, San Francisco

Abstract

Mutations in short linear motifs impair the functions of intrinsically disordered proteins in cellular signaling/regulation and contribute substantially to human diseases.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MB/C4MB00290C

Reference113 articles.

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4. A Disease State Mutation Unfolds the Parkin Ubiquitin-like Domain

5. Catalytic Inactivation of Human Phospholipase D2 by a Naturally Occurring Gly901Asp Mutation

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