Sustainable strategies based on glycine–betaine analogue ionic liquids for the recovery of monoclonal antibodies from cell culture supernatants-Reference-Cited by-同舟云学术

Sustainable strategies based on glycine–betaine analogue ionic liquids for the recovery of monoclonal antibodies from cell culture supernatants

Published:2019 Issue:20 Volume:21 Page:5671-5682
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Capela Emanuel V.¹²³⁴⁵^ORCID,Santiago Alexandre E.¹²³⁴⁵,Rufino Ana F. C. S.¹²³⁴⁵,Tavares Ana P. M.¹²³⁴⁵,Pereira Matheus M.¹²³⁴⁵^ORCID,Mohamadou Aminou⁶⁷⁸⁹¹⁰^ORCID,Aires-Barros M. Raquel¹¹¹²¹³¹⁴¹⁵,Coutinho João A. P.¹²³⁴⁵^ORCID,Azevedo Ana M.¹¹¹²¹³¹⁴¹⁵,Freire Mara G.¹²³⁴⁵^ORCID

Affiliation:

1. CICECO – Aveiro Institute of Materials

2. Department of Chemistry

3. University of Aveiro

4. 3810–193 Aveiro

5. Portugal

6. ICMR – Institute of Molecular Chemistry of Reims

7. University of Reims Champagne-Ardenne

8. CNRS UMR 7312

9. UFR des Sciences Exactes et Naturelles

10. F51687 Reims cedex 2

11. iBB – Institute for Bioengineering and Biosciences

12. Department of Bioengineering

13. Instituto Superior Técnico

14. Universidade de Lisboa

15. 1049–001 Lisbon

Abstract

Ionic-liquid-based aqueous biphasic systems, three phase partitioning methods and hybrid processes combined with ultrafiltration are sustainable strategies for the downstream processing of monoclonal antibodies.

Funder

European Cooperation in Science and Technology

Horizon 2020 Framework Programme

Fundação para a Ciência e a Tecnologia

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC02733E

Reference51 articles.

1. E. V. Capela , M. R.Aires-Barros , M. G.Freire and A. M.Azevedo , Frontiers in Clinical Drug Research-Anti Infectives , 2017 , vol. 4 , pp. 142–203

2. A. Hey , in Antibodies for Infectious Diseases , American Society of Microbiology , 2015 , pp. 3–21

3. Aqueous two-phase systems: A viable platform in the manufacturing of biopharmaceuticals

4. The therapeutic monoclonal antibody market

5. The Increasingly Human and Profitable Monoclonal Antibody Market

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